WebJan 2, 2007 · Background: S100B is considered an astrocytic in-situ marker and protein levels in cerebrospinal fluid (CSF) or serum are often used as biomarker for astrocytic damage or dysfunction. However, studies on S100B in the human brain are rare. Thus, the distribution of S100B was studied by immunohistochemistry in adult human brains to … WebMay 24, 2024 · The role of the S100 protein family in this interplay remains unclear and is the aim of this research. Intracellularly the S100B protein has a protective effect on neurons against the toxic effects of glutamate and stimulates neurites outgrowth and neuronal survival. At high concentrations, it can induce apoptosis.
S100B dysregulation during brain development affects synaptic
WebThe rupture of the blood–brain barrier (BBB) and either damage to the neurons and glia of the spinal cord tracts results in the release of biomarkers, largely cellular components, which are specific in the indication of nervous tissue damage and include neurofilaments (NF), S100 calcium-binding protein β (S100β) and glial fibrillary acidic ... WebObject: During recent years, several biomarkers have been introduced for use in the diagnosis of traumatic brain injury (TBI). The primary objective of this investigation was to determine if S100B (or S100 calcium-binding protein B) and neuron-specific enolase (NSE) serum concentrations can effectively be used to discriminate between … pay chicago parking tickets by phone
S100B protein: general characteristics and pathophysiological …
WebS100B is a member of the S100 protein family. It is a cytosolic calcium-binding protein concentrated in astrocytes, and therefore is released following astroglial injury. S100 is … WebResults: Due to its ability to bind with calcium, S100B is involved in the regulation of several intra- and extracellular physiological processes. As well as being multifunctional, this … WebRecent advances in perioperative management of adult and pediatric patients requiring open heart surgery (OHS) and cardiopulmonary bypass (CPB) for cardiac and/or congenital … pay chicago speeding ticket