WebDec 24, 2024 · The protective effects of chlorogenic acid (CGA) against liver injury were evaluated by its reduction in carbon tetrachloride (CCl4)-induced hepatic damage in ICR mice. The animals were orally given CGA (60, 100, and 200 mg/kg, respectively) or silymairn (200 mg/kg) daily with 0.3% CCl4 administration (3 mL/kg, dissolved in olive oil) … Webcarbon tetrachloride, also called tetrachloromethane, a colourless, dense, highly toxic, volatile, nonflammable liquid possessing a characteristic odour and belonging to the family of organic halogen compounds, used principally in the manufacture of dichlorodifluoromethane (a refrigerant and propellant).
Effects of Medicinal Plants on Carbon Tetrachloride-Induced Liver ...
WebCCl 4 is a powerful hepatoxic, nephrotoxic and prooxidant agent which is widely used to induce hepatotoxicity in experimental animals and to create hepatocellular carcinoma, hepatic fibrosis/cirrhosis and liver injury, chemical hepatitis model, renal failure model, and nephrotoxicity model in recent years. WebHepatoprotective herbs against carbon tetrachloride‑induced liver toxicity Medicinal plants Key findings References Acalypha wilkesiana • Transaminase, ALP, lactate dehydrogenase, gamma‑glutamyl transferase, [11] urea, and creatinine levels in the blood were all significantly reduced by the extract. cliche kid carol ann duffy analysis
Why does carbon tetrachloride not dissolve in water? - Quora
WebProduct name : Carbon tetrachloride Product Number : 571016 Brand : Aldrich Index-No. : 602-008-00-5 CAS-No. : 56-23-5 1.2 Relevant identified uses of the substance or mixture and uses advised against ... Specific target organ toxicity - repeated exposure, Inhalation (Category 1), Liver, Kidney, H372 Short-term (acute) aquatic hazard (Category ... WebThe latter process has been implicated as a major mechanism of CCl4 hepatoxicity, although this relationship has been difficult to demonstrate when using isolated hepatocyte preparations. This report demonstrates that there are at least two mechanisms by which CCl4 induces injury in isolated hepatocytes. WebHepatotoxicants may include industrial chemicals, certain drugs, microcystins, dietary supplements, and herbal remedies.[3,4] Carbon tetrachloride (CCl 4)-induced liver injury results from the toxic metabolites of CCl 4 that cause centrilobular hepatic necrosis and steatosis and impair essential cellular processes. bmw dealership in houston tx