WebProduct Name. Target. Research Areas. HY-114409. GB1107. Galectin. Cancer. GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for … WebBiological Activity. GB1107 (GB-1107, GB 1107) is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with Kd of 37 nM (human Galectin-3). GB1107 displays >100-fold lower affinity for most of the tested human galectins, and 20 and 4-fold lower affinity for galectin-2 and the C-terminal CRD of galectin-4, respectively.

GB1107 (GB-1107) CAS 1978336-61-6 - AbMole

GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model. - Mechanism of Action & Protocol. WebGB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. In vitro activity: Additionally, the exposure of LNCaP cells to 2 … おかげ参り 犬

Combination therapy with galectin-3 inhibitor GB1107 …

WebSep 11, 2016 · GB1107 (10mg/kg) significantly reduced the fibrosis score. and decreased the number of macrophages and collagen concentration in the BAL fluid with decreased surface expression of galectin-3 on BAL macrophages. GB1211 at 20 mg/kg twice daily reduced collagen accumulation by 36%. WebDescription GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model[1]. IC₅₀ & Target Kd: 37 nM (human Gal-3)[1]. Product Data Sheet Inhibitors • Screening Libraries • Proteins Web参照《渔业水质标准》（gb1107-89）中所列的部分项目和相应的方法执行，见表2。 7.3用于建筑测试指标的测试方法： 地基承载力：参照《建筑地基基础设计规范》（GBJ7-89）中第五章、第六章及附录四（地基土载荷试验要点）、附录五[土（岩）承载力标准值 ... paperone numero 1