Thiotepa (INN ), sold under the brand name Tepadina, is a medication used to treat cancer. Thiotepa is an organophosphorus compound with the formula (C2H4N)3PS. It is an analog of N,N′,N′′-triethylenephosphoramide (TEPA), which contains tetrahedral phosphorus and is structurally akin to phosphate. It is … See more Thiotepa is indicated for use in combination with other chemotherapy agents to treat cancer. This can be with or without total body irradiation (TBI), as a conditioning treatment prior to allogeneic or autologous See more The main side effect of thiotepa is bone marrow suppression resulting in leukopenia, thrombocytopenia and anemia. Liver and lung toxicity may also occur. See more • "Thiotepa". Drug Information Portal. U.S. National Library of Medicine. See more Thiotepa was developed by the American Cyanamid company in the early 1950s and reported to media outlets in 1953. In 1959, thiotepa was … See more WebThiotepa (also known as Thioplex ®) is an anticancer medicine. It is a clear liquid given by vein (IV). Thiotepa can pose a health hazard to caregivers. All caregivers should take safety precautions while giving this drug. For 48 hours after this drug is given, the patient’s body fluids can contain the drug.
Effect of ThioTEPA on the Synthesis of Protein and Nucleic Acids …
WebCarmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA production and RNA translation (protein synthesis). Carmustine also binds to and modifies (carbamoylates) glutathione reductase. This leads to cell death. ... Thiotepa: The risk or severity of adverse effects can be increased when Carmustine is ... WebTreatment with three daily doses (3-10 µg/gm each) of thioTEPA inhibited incorporation of … shoe pole used at payless
Thiotepa: Package Insert - Drugs.com
WebThiotepa C6H12N3PS CID 5453 - structure, chemical names, physical and chemical … WebThiotepa / chemical synthesis Thiotepa / chemistry Thiotepa / toxicity United States Substances Antineoplastic Agents, Alkylating Carcinogens Thiotepa ... WebNov 27, 2016 · English: Chemical synthesis of thiotepa. Created with ChemDoodle and Adobe Illustrator CC 2024. Date: 27 November 2016: Source: Own work: Author: Vaccinationist: Permission (Reusing this file) Public domain Public domain false false: This image of a simple ... shoe pokemon cards